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Once bound, it activates the PI3K/Akt and mTOR pathways , which regulate: Protein synthesis (muscle building) Cell proliferation and differentiation Glycogen storage Fat metabolism In simpler terms: IGF-1 LR3 tells your muscles to grow , recover , and use nutrients more efficiently but it also stimulates cell growth everywhere, not just in muscles
Clinically observed reductions in lean mass during medically induced weight loss [40] are therefore consistent with a substrate-sensitive vulnerability affecting skeletal muscle maintenance
Women tell us that the structure makes it easier to stay consistent even on busy weeks because they do not have to guess what to train
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