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The assay was designed to demonstrate the biochemical activity of c-met binding sites including Y198 and Y250 (in K1 and K2 domains of HGF, respectively) by significant changes in optical absorbance (expressed as relative unit) within a range from a baseline level (a negative control without HGF
Bekris, J
This profile supports once-weekly subcutaneous administration, similar to other long-acting GLP-1-based therapies already in clinical use
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