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Jump to: Comparison at a glance | Tirzepatide (Mounjaro) | Semaglutide (Wegovy) | Liraglutide (Saxenda) | NHS vs private access | Side effects comparison | Cost analysis | How to choose | Medications in development | Frequently asked questions | Take home message Based on clinical trial data, the most effective weight-loss injection available in the UK in 2026 is tirzepatide (Mounjaro), with an average weight loss of 22.5% of starting body weight after 72 weeks at the maximum 15 mg dose
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Plasma levels decline with age, which is part of why it became a research target for skin, hair, and wound healing
Research shows it can raise blood glutathione levels 20 times more than standard forms and even reduce blood mercury by 39% within 30 days
