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MOTs-C has potential side effects similar to other injectable medications

And protein kinase A phosphorylates hormone-sensitive lipase, the enzyme that physically breaks triglycerides apart into free fatty acids and glycerol

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Its job is specific: it inhibits an enzyme called NNMT nicotinamide N-methyltransferase that becomes overactive in fat tissue, especially as we age

It does not directly stimulate fibroblast proliferation under normal culture conditions, but substantially increases fibroblast survival under hydrogen peroxide-induced oxidative stress acting as a cytoprotective enhancer of the endogenous repair response rather than a direct mitogenic agent