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When tumor cells derived from the LT2MYC model are transfected with locked nucleic acid (LNA) antagonists against miR18a, we observe that GCLC protein expression increases relative to cells treated with control LNA (Fig 3E)

As a class effect shared with GLP-1 receptor agonists, there is a precautionary concern regarding thyroid C-cell tumours, based on animal studies

Rebates are usually based on a percentage of a drugs list price, which means the higher the price, the bigger the rebate

Sometimes, but stacking should follow a clear rationale and include monitoring

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