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Altering substituents on the aromatic rings can significantly change binding affinity to NNMT
If you are making a subcutaneous injection just under your skin, pinch the area where you will be taking the shot
Not because they're unsafe, but because the weight loss magnitude in controlled trials wasn't commercially viable compared to GLP-1 agonists or other obesity drugs
The compound is supplied as a lyophilized white-to-off-white powder in a sealed amber-glass vial under inert gas
Biochemical Pharmacology (2018) 2
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