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HRT Addresses: Estrogen-driven fat redistribution, muscle loss prevention, sleep disruption, hot flashes and night sweats GLP-1 Addresses: Appetite dysregulation, insulin resistance, blood sugar instability, inflammation reduction Combined Benefit: Targets both hormonal AND behavioral factors, which can help preserve lean mass while losing fat and support better energy for lifestyle changes, leading to comprehensive quality of life improvement Rather than competing approaches, hormone optimization therapy and GLP-1 therapy can work through distinct physiological pathways that reinforce each other

Here's what I'll tell you: the skepticism is healthy, the research is real, and yes, I prescribe it in my Houston practice

But research also shows that collagen supplements you take by mouth may help your skin stay moist and elastic, especially if you're older than 30

10.1074/jbc.RA118.002713 277 HuZ

OBrien M, Chalker J, Slade L, Gardiner D, Mailloux RJ