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TB-500 Pharmacodynamics : TB-500 is a fragment of Thymosin Beta-4, which facilitates cellular movement and tissue regeneration by modulating actin polymerization and promoting angiogenesis ( 6, 8 )

Examination of the GST-GFP reporter, which contains multiple anti-oxidant response elements (ARE) and is activated in oxidized tissue 38 , shows robust activations in APAP-exposed animals (Fig