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Tsujii S, Ishisaka M, Shimazawa M, Hashizume T, Hara H

When IGF-IR is deleted in mature osteoblasts, using OCN promoter-driven Cre line, the KO mice produce less trabecular bone, with an increased proportion of osteoid in the bone, indicating impaired mineralizing functions in OCN IGF-IR / osteoblasts (58,59)

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