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During treatment with trial product (any dose of trial medication administered within the previous 2 weeks (that is, any period of temporary treatment interruption with trial product was excluded))

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To induce expression of proteins under a doxycycline-inducible promoter (pTRE3G), cells were incubated with medium supplemented with 100200 ng ml 1 doxycycline overnight

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For someone losing weight rapidly on a GLP-1 medication, suboptimal vitamin D compounds the already-present risk of losing muscle alongside fat