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This reduction in anti-inflammatory signaling could prevent the repolarization of CAR macrophages from a pro-inflammatory (M1) state back to an immunosuppressive (M2) state, thus maintaining their tumoricidal activity and reinforcing their ability to promote a sustained anti-tumor immune response

Reduced glutathione also known as glutathione or GSH is found in all living systems.[1] Lowered tissue GSH levels have been observed in several disease conditions.[2] The restoration of cell GSH levels in a number of these conditions have proven to be beneficial

Sikiric P (2022)

Traumatic brain injury in mice and pentadecapeptide BPC 157 effect

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