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During initial dose escalation, transient dyspepsia and regurgitation occurred, out of caution semaglutide treatment was continued at a lower dose of 0.5 mg weekly for the following five months, which led to a weight reduction of 8 kg

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Even more impressively, the SELECT trial tracked over 17,000 participants for an average of nearly three and a half years and not only confirmed the medication's safety but also showed it reduced major cardiovascular events by 20% compared to placebo

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