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In one clinical trial in people with type 2 diabetes, the weight loss became noticeable as early as week five, with participants taking Zepbound having lost nearly 6 pounds (compared with only about 2 pounds for those taking a placebo)
Further clarification is needed on the appropriate supplemental dose and corresponding time points
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Summary: Weight gain on Ozempic can occur due to medication interactions, underlying endocrine conditions, fluid retention, dietary compensation, subtherapeutic dosing, or metabolic adaptation despite semaglutide's typical weight-reducing effects
Giraldo-Grueso, M
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