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For individuals seeking support with obesity or weight management, NICE-approved pathways exist and should be the starting point

The most common side effect is irritation at the site of injection which could last up to 5-10 minutes

Naturopathic doctors licensed in Canada sometimes have more experience with peptide protocols and can provide guidance within their scope of practice

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By activating glucagon signaling in the liver, Retatrutide increases resting metabolic rate and mobilizes hepatic lipid stores, contributing to both weight loss and improvements in metabolic dysfunction-associated steatotic liver disease (MASLD) (Sanyal et al., 2024