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Acne scars: Post-inflammatory hyperpigmentation leaves dark marks even after acne clears
Lord, C
In RA patients, an alteration of DNA methylome signature in PBMC and a reduction of 5-mC amounts in synovial tissues were observed, the alteration of FLS gene expression, including chitinase-3-like protein 1 (CHI3L1), caspase 1 (CASP1), STAT3, mitogen-activated protein kinase kinase kinase 5 (MAP3K5), familial Mediterranean fever (MEFV), and wnt1-inducible signaling protein 3 (WISP3), is caused by differentially methylated genes leading to the pathogenesis of RA (293)
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Such glucose and oxygen deprivation can lead to decreased MHC class I antigen presentation in cancer cells, rendering them unresponsive to IFN-mediated cytotoxic effects due to STAT1 dysfunction
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