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GLP-1 (the same target as semaglutide) slows gastric emptying and increases satiety

This approval was based on clinical trials that showed significant loss in body weight when compared to a placebo after a year of treatment for non-diabetic individuals and those with type 2 diabetes

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[1] [9] Sermorelin , by contrast, was FDA-approved decades ago (Geref, 1997) but the manufacturer voluntarily withdrew it in 2008, and the FDA determined that withdrawal was not for reasons of safety or effectiveness