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These findings suggest that a mechanism similar to that observed in mice [10] is at work in humans and that combining metformin with DPP-4 inhibitors appears to be a rational way of enhancing GLP-1 signalling in pancreatic beta cells
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The prescriber may need to reduce doses of these concurrent medications to minimise hypoglycaemia risk whilst maintaining overall glycaemic targets
Reactive oxygen species as mediators of sperm capacitation and pathological damage
J Invest Dermatol 129:15271538
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