Although moderate levels of ROS act as signaling molecules in cellular processes such as differentiation, proliferation, and adaptive responses [153], excessive ROS accumulation induces lipid peroxidation, protein modification, and mitochondrial DNA damage, ultimately leading to cellular senescence, apoptosis, or dysfunction [154]
Dendritic cells as shepherds of T cell immunity in cancer
They can be utilized for the direct and indirect detection of antigens in various assays, as capture molecule immobilized on microplates, or as ligand for protein purification
In this study, we sought to investigate the role of cystine in the regulation of mTORC1, the ISR and ferroptosis and whether GSH is an important determinant in the regulation independent of its reducing capacity
It also reduces the dark circles under the eye