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The strongest reported weight-loss data so far come from Lillys 2026 TRIUMPH-1 phase 3 topline results and earlier phase 2 obesity data [4], [7]
Beginner guidelines for GLP-1 users: Start with 2 sessions per week, full-body format Use machines or guided dumbbell exercises to learn movement patterns safely Keep weights moderate: you should be able to complete all reps with controlled form Progress to 3 sessions per week after 3-4 weeks Transition to barbell and free-weight movements as confidence and form improve Do not rush
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