Using data from the World Health Organization, they performed a disproportionality analysis, which sought to determine whether there were more reports of suicidal ideation in people taking GLP-1 drugs than would be expected compared to other types of drugs that people with obesity are commonly prescribed, like metformin (13)
Effect of age, sex, and morbidity count on trial attrition: meta-analysis of individual participant level data from phase 3/4 industry funded clinical trials
Foods High in Glutamine to Add to Your Diet. Livestrong, October 2021, Coqueiro, Audrey Yule et al
This broadened inclusion criteria allowed for a more comprehensive understanding of drug effects in high-risk groups and supported the expansion of GLP-1R agonist indications beyond glycemic control to include cardiovascular and renal benefits
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