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Benefits of B12 supplementation have been shown in a number of conditions, including diabetic neuropathy, back pain, mouth ulcers, autism spectrum disorder and elevated homocysteine levels, and it is generally considered to be very safe even at high dosages
Results are typically gradual and progressive
Thiamine deficiency is of specific clinical concern due to its role in neurological and GI function
Long-term considerations Short-term results are one thing
However, vitamins may contain higher doses of 50 to 500 mcg and 1,000 to 2,000 mcg tablets are available
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