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Reassess gut markers (e.g., zonulin, calprotectin) every 812 weeks under medical supervision

This review highlights NAD+ as a central regulator of energy metabolism, mitochondrial function, and cellular repair, demonstrating that age-related declines in NAD+ may contribute to chronic disease, while supplementation with NAD+ boosters shows potential for reducing age-related decline and disease

Kelsey MD, Nelson AJ, Green JB, Granger CB, Peterson ED, McGuire DK, et al

Hormones present during menstruation do not reduce the drug's effectiveness or increase serious adverse events

The dosage and delivery (supplement versus intramuscular injection) should be personalized to the individual and adjusted as lab levels change