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Comparisons between the transgenic GSAAT1 substitution mutants and wild-type GSAAT1 expressed in the gsa2 background revealed a slightly reduced ALA synthesis capacity of leaf discs and in planta GSAAT activity of the leaf extracts only for the GSAAT(C190S) line ( Supplementary Figures 3C, E )

Dizziness may result from hypoglycaemia (especially when combined with other diabetes medications), dehydration from gastrointestinal side effects, reduced caloric intake, or orthostatic hypotension

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Clinical trials show GLP-1 receptor agonists reduce waist circumference by approximately 13.5 cm with semaglutide after 68 weeks, with imaging studies demonstrating significant decreases in visceral adipose tissue volume