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What if these agents are psychiatric drugs that are masquerading as weight-loss drugs? Roger McIntyre More research is needed to confirm any potential connection between GLP-1 agonists and mental health, but several trials are ongoing
[Accessed 10 Feb 2026] Hypoglycaemia (2023) NHS [Accessed 20 January 2026] Tirzepatide once weekly for the treatment of obesity (2022) JAMA
Ozempic vulva emerged online to group anecdotal vaginal changes and visible skin changes after significant weight loss on GLP-1 drugs like Ozempic
They may have relapses, but most are benign
But for the patient sitting in front of me today, I need a drug I can prescribe, that they can fill at their pharmacy, and that their insurance will cover." Switching from Liraglutide to Retatrutide No clinical protocol exists for switching between these two agents because retatrutide is not yet approved
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