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This is thought to be related to GLP-1s effects on the brains dopamine reward pathway, says Nitya Kumar, MD, an endocrinologist and an assistant professor of medicine at the Duke University School of Medicine in Durham, North Carolina

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Some patients start with brand-name at the $199 introductory price for the first two months, then switch to compounded at $199 ongoing to maintain the lowest cost

Many psychiatristsparticularly those treating serious mental illness in patients on long-term antipsychotic therapyare now prescribing GLP-1 RAs

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