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Protein-tyrosine nitration is a post-translational chemical modification process for the highly selective non-enzymatic introduction of a nitro group (-NO 2 ) into the side chain by peroxynitrite (ONOO - ), a short-lived biomolecule generated by the rapid reaction of NO with superoxide radicals in vivo 40,41

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Practically, achieving and eliminating poverty in all its forms remain the greatest challenge facing humankind despite significant interventions (Ngcobo et al., 2025)

For example, consistency between serum and plasma samples has not been achieved for the same Klotho assay or among different Klotho assays (Heijboer et al., 2013)

Clin Nephrol 2003;59(1):24-30