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Inhibition of non-CYP enzymes especially UDP-glucuronosyltransferases (UGTs) significantly predicts high risk for drug-induced liver injury (DILI)
doi: 10.1056/NEJMp2400978 Summary Keywords GIP, GLP-1, GLP-1RA, tirzepatide, diabetes, obesity, cardiovascular disease Citation Liu QK (2024) Mechanisms of action and therapeutic applications of GLP-1 and dual GIP/GLP-1 receptor agonists
Is Longevity Support also suitable for humans
They may also be preferred in patients with elevated glycemia levels and high BMI aiming at modifying CV risk factors ( GLP-1 RAs have a favorable safety profile
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