Statistical analysis was performed ANOVA (to analyse the difference between the means of more than two groups) or Students t test (to compare the means of specifically two groups), after normality was assessed by a Shapiro-Wilk test
HR 0.64, 95% CI 0.460.88
[13] Conversely, significant energy deficit and rapid weight loss can temporarily suppress reproductive hormones a phenomenon recognised in functional hypothalamic amenorrhoea potentially reducing sexual drive in some individuals (see NICE CKS: Amenorrhoea)
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The synergy among these peptides promotes angiogenesis, fibroblast proliferation, and connective tissue integrity , while also minimizing fibrosis and scarring
