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In the Pharmacologic Approaches to Glycemic Treatment: Standards of Care in Diabetes published in 2024, it was recommended to start GLP-1 RA sodium-glucose co-transporter 2 inhibitors (SGLT2i) in patients with T2DM and ASCVD, while also commenting upon noted benefit in specifically HFpEF as well [53]

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Framed honestly, this is a case where a compounds breadth of action is simultaneously an interesting pharmacological feature and a limitation for anyone seeking a clean, GH-only signal

Contribution statement All authors were responsible for drafting the article and for critically revising it for substantial intellectual content

This network connects the ventral tegmental area (VTA) to the nucleus accumbens and is responsible for the hit of pleasure you feel when eating something delicious, receiving good news, or critically consuming alcohol or other addictive substances