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BPC-157 demonstrates exceptional safety in animal toxicology studies, with comprehensive evaluations in mice, rats, rabbits, and dogs failing to establish a lethal dose (LD) across wide dose ranges extending from standard research doses (6 g/kg) to levels exceeding 1000-fold higher concentrations (20 mg/kg), with no evidence of acute toxicity, organ-specific damage, or systemic adverse effects even following repeated high-dose administration

Thats a long half-life, it can exert its pharmacological actions in the hosts body for the same duration

Next to NAD + precursors, modulation of NAD + -consuming enzymes showed promising results

283 , E899E908 (2002)