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In clinical trials, tirzepatide demonstrated greater A1c reduction and weight loss compared to semaglutide 1 mg, though individual responses vary considerably

In concordance with homeostatic processes, the mesolimbic system contributes to food-related motivation and its dysregulation underlies disturbances in food preoccupation (that is, heightened or persistent reactivity to food cues 11 )

Lpez-Ojeda W and Hurley RA

Many people can transition from compounded tirzepatide to FDA-approved Zepbound with a clinician-guided plan

Set your milestones: You and your provider might want to agree on a point at which you reconsider medication