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doi: 10.2337/dc23-1791 Summary Keywords metformin, semaglutid, PCOS, obesity, maintenance, weight regain Citation Jensterle M, Ferjan S and Janez A (2024) The maintenance of long-term weight loss after semaglutide withdrawal in obese women with PCOS treated with metformin: a 2-year observational study
The treatment involved intravenous DSIP administration on five consecutive days, followed by five injections every 48-72 hours
Additionally, IGF-1 levels were reported to rise by about 28%, hinting at an improved functionality of the growth hormone-IGF-1 axis
A systematic review in 2025 identified one qualifying clinical study: a retrospective analysis in which 7 of 12 subjects with chronic knee pain reported relief for over six months following intra-articular injection
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