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Test subjects were randomly assigned to one of nine experimental treatments including once-weekly semaglutide in doses of 0.1, 0.2, 0.4, or 0.8 mg, once-weekly semaglutide with dose escalation (E) (0.8 or 1.6 mg E), once-daily active control (1.2 or 1.8 mg), or once-weekly placebo
These ingredients work together to break down lipid cells
In the UK, these higher-dose formulations are available through specialist weight management services for people meeting specific BMI thresholds and with weight-related comorbidities, as outlined in NICE technology appraisals
Maintaining adequate fluid intake helps manage potential side effects such as constipation, which is common with GLP-1 medications, and supports overall physiological function
