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Similar changes in oxidation state of GCL were also observed with other oxidative stress treatments, including cadmium exposure, inhibition of glutathione synthesis by buthionine sulfoximine, or the generation of reaction oxygen species via menadione (Hicks et al., 2007)

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GSH Concentration = Total Glutathione Concentration - [GSSG Concentration] x 2 *One molecule of GSSG (oxidized glutathione) is equivalent to two molecules of GSH (reduced glutathione)

Due to specific riboflavin demands of women linked to pregnancy, iron deficiency, hormonal homeostasis, contraceptive use, and other physiological and lifestyle aspects, it is crucial to ensure an adequate riboflavin status