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Among the available clinical data in human subjects, in 2012 one case report showed that pioglitazone treatment could have some positive effects in radioiodine-negative and progressive DTC patients (Rosenbaum-Krumme et al., 2012)
Efficacy: the biggest uncertainty One of the biggest unanswered questions around oral GLP-1s is not convenience or appeal, but effectiveness
AS BILL AND others have found, real semaglutide is difficult to get
Whether starting with microdose therapy or full-strength semaglutide, continuous use without planned discontinuation produces the most reliable weight maintenance outcomes supported by clinical evidence
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