does a higher dose of semaglutide mean more weight loss for Loss: How It Works, Comparisons, and Wegovy vs. Ozempic: What To

These include: Nausea (affecting 2040% of patients initially) Vomiting and diarrhoea Constipation Abdominal discomfort or bloating Reduced appetite These symptoms are usually mild to moderate and tend to diminish over several weeks as the body adjusts to the medication

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It enrolled 3,731 adults over 56 weeks and found: 3 -8.0% average body weight loss (vs -2.6% with placebo) 63.2% achieved 5% weight loss (vs 27.1% with placebo) 33.1% achieved 10% weight loss (vs 10.6% with placebo) These results show liraglutide is effective compared with placebo, but less effective than semaglutide at weight-management doses

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Instead of asking whether GLP-1 medications work, clinicians are beginning to ask for whom they work best and what alternative pathways should be considered when responses are incomplete. We asked our experts to explain why GLP-1s dont always work for weight loss and what alternatives are available