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Built for Higher Stability: Cyclization (AspLys lactam bridge) plus amino-acid substitutions (e.g., Nle , D-Phe ) help reduce enzymatic breakdown in experimental systems

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Read the article: #SPR #MembraneProteins #Biacore #DrugDiscovery #ProteinCharacterization #LifeSciences To view or add a comment, sign in Membrane proteins are central to drug discovery, representing a large share of todays therapeutic targets

The following reflects current understanding based on phase 2 data and the established safety profiles of approved GLP-1 receptor agonists per UK Summary of Product Characteristics (SmPCs)