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Rather than focusing solely on calorie counting, aim for a diet rich in: Lean proteins (chicken, fish, legumes, eggs) which support satiety and help preserve muscle mass during weight loss, which is particularly important given that GLP-1-based therapies may reduce lean mass alongside fat if protein intake is insufficient Fibre-rich vegetables and wholegrains which slow gastric emptying and complement the drug's appetite-suppressing effects Healthy fats (olive oil, avocado, nuts) in moderate quantities to support hormonal health Minimally processed foods reducing reliance on ultra-processed products that are engineered to override satiety signals If you have chronic kidney disease or other conditions affecting protein metabolism, speak to your clinical team before significantly increasing protein intake

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This principle of combinatorial modification is central to modern peptide research and explains why so many new therapeutic peptides are engineered variants of natural hormones