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FOXO4-DRI Also known as: FOXO4 D-Retro-Inverso, Proxofim Summary FOXO4-DRI is a senolytic peptide built in mirror-image (D-retro-inverso) form for stability, designed to kill senescent "zombie" cells by breaking the FOXO4-p53 interaction that keeps them alive
However, this interaction is generally manageable
demonstrated sympathomimetic mechanisms to be responsible for inotropic and chronotropic effects in murine models in vivo, and others such as Ahren et al
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