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The known recessive genetic defects that cause homocystinuria are summarized here: Cystathionine -synthase deficiency Homocysteine, in its oxidized disulfide form (Figure 1), was first detected in the urine of two siblings with intellectual disability in Ireland in 1963 (29)

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The treatment of asthma generally involves a combination of therapies, such as inhaled corticosteroids, anticholinergics, short-acting -agonists, and long-acting -agonists [1, 31]

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Authors Note : To push back slightly on Breckas framing peptides work because they successfully bind to specific cell receptors, not because the body recognises them as endogenous metabolites