Additional studies show BPC-157 modifies signaling of focal adhesion components such as focal adhesion kinase (FAK) and paxillin, critical for cell migration, attachment, and wound closure
It also cites an unnamed 2023 observational study reporting larger pain-score improvements at higher weight loss, but since that study is never identified, its specific figures cannot be verified
ROS is a key regulator of both apoptosis and autophagy
To me the biggest concern is that these companies appear to be promoting a lifelong duration of therapy, as evident by their zero attention to getting people off the drugs, without reverting back for both weight gain and risk of adverse outcomes
However, in Sprague Dawley rats, GLP-1 monotherapy significantly increased kaolin intake compared with vehicle-treated rats and rats treated with MK-801 (Extended Data Fig