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GLP-1 users may differ from nonusers in ways that are not fully captured, such as socioeconomic status, health behaviors, disease severity, medication adherence, or access to care." Lakkis notes that the study also did not report how much weight participants lost, making it difficult to determine how much of the benefit may have been driven by weight reduction itself

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Patients with glutathione synthetase deficiency accumulate the dipeptide -glutamylcysteine and cysteine in fibroblasts [24]

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