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Once these meds are on board, they cozy up to the receptors spread out in spots like the pancreas and our noggin

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Constipation may allow the medication to sit in the body longer and be absorbed more, [while] vomiting and diarrhea may rid the body of the medication [more] quickly before it has time to reach its maximal effect. Finally, although your body weight wont affect the metabolism of Wegovy, your overall body mass index (BMI) and muscle tissue can play a part