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Local tolerability of intravenously administered alpha-lipoic acid
GLP-1 binds to its specific receptor (GLP1R), promoting insulin release
Funding Open access funding provided by Universit degli Studi di Napoli Federico II within the CRUI-CARE Agreement
In preclinical models, apelin enhances glucose uptake in skeletal muscle via activation of AMP-activated protein kinase, improves insulin sensitivity, and increases mitochondrial oxidative capacity, supporting its role as an endogenous insulin-sensitizing hormone (Dray et al., 2008)
Individual biology drives the response
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