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If symptoms show little improvement after 36 months and your lab results remain stable, your healthcare provider may consider a cautious dose increase - often moving from 50100 mg/day to 100200 mg/day

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Particular focus was on IcoSema, a new drug by Novo Nordisk that combines once-weekly insulin icodec (approved in Europe and other countries, but not yet the U.S.) and semaglutide, a GLP-1 agonist