According to Harvard Medical School, people with cobalamin deficiency may experience subtle but unusual and progressive signs of illness, including strange tingling or numb sensations, difficulty walking, cognitive and memory issues, and weakness
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General wellness and anti-aging: 2.0 to 4.0mg total daily, which translates to 10 to 20 units if reconstituted at 20mg/mL
And one of the best examples is really the HIV PEP and PrEP