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Nitric oxide release in turn supports vasodilation, which has been proposed as a contributor to the perfusion-related findings in tissue-injury models

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If bleeding has been frequent or prolonged, checking for iron deficiency anaemia (with blood tests for full blood count and ferritin) may be appropriate, with iron supplementation if indicated

While there is not yet an official Daily Value (recommendations aimed at avoid deficiency states), Adequate Intake (AI) levels for choline were established by the National Academy of Sciences in 1998

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