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There are a number of cutaneous findings to be aware of when encountering these drugs
Functionally, GLP-1 plays an important role in energy homeostasis and nutrient absorption
Available online at: (accessed July 29, 2022)
Periodic MC1R stimulation prevents downregulation of tyrosinase expression and melanosome transport machinery, keeping melanocytes primed for eumelanin synthesis
It should be noted that the extent of weight loss achieved with GLP-1RA add-on to SGLT2i appears anyway modest compared to the efficacy of newer treatments for weight management, including dual incretin receptor agonists
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