Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist belonging to the incretin mimetic class
State DMSO stock solution (lab) Storage -112F (-80C) ideal
They enhance glucose-dependent insulin secretion, suppress glucagon release, and slow gastric emptying, while supporting the preservation of pancreatic beta-cell function
Patients may notice reduced weight loss results or no appetite suppression at all
General disorders and administration site conditions: Swelling of the face or tongue, allergy, anaphylactic/anaphylactoid reactions, hypothermia Skin and subcutaneous tissue disorders: Rash, dermatitis, urticaria, eczema, toxic epidermal necrolysis, Stevens-Johnson Syndrome, erythema multiforme [see Warnings and Precautions (5.1)] Gastrointestinal Disorders: Gastrointestinal bleeding, hemorrhagic colitis Cardiac Disorders: Arrhythmia Hepatobiliary Disorders: Hepatitis, abnormal liver function tests Nervous System Disorders: Seizure Metabolism and Nutrition Disorders: Aggravation of diabetes Psychiatric Disorders: Abnormal behavior, delirium, including symptoms such as hallucinations, agitation, anxiety, altered level of consciousness, confusion, nightmares, delusions [see Warnings and Precautions (5.2)] 7