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The short answer is this: retatrutide looks promising for body composition, but current research does not prove that it directly builds muscle or fully prevents muscle loss

Its comparison with semaglutide and cardiovascular outcomes will define its benefits, potentially impacting long-term complications of type 2 diabetes

However, injectable semaglutide may be more convenient for patients who wish to administer a weekly injection rather than keep up with a daily dose of medication

Its being studied for both diabetes and weight management, with an FDA decision expected in late 2026

She enrolled in a trial at Penn Medicine testing deep brain stimulation as a way to stop cravings before they start